Dietary Microbial Metabolites, Short-chain Fatty Acids and Host Energy Regulation
نویسندگان
چکیده
منابع مشابه
Dietary Gut Microbial Metabolites, Short-chain Fatty Acids, and Host Metabolic Regulation
During feeding, the gut microbiota contributes to the host energy acquisition and metabolic regulation thereby influencing the development of metabolic disorders such as obesity and diabetes. Short-chain fatty acids (SCFAs) such as acetate, butyrate, and propionate, which are produced by gut microbial fermentation of dietary fiber, are recognized as essential host energy sources and act as sign...
متن کاملFrom Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
A compelling set of links between the composition of the gut microbiota, the host diet, and host physiology has emerged. Do these links reflect cause-and-effect relationships, and what might be their mechanistic basis? A growing body of work implicates microbially produced metabolites as crucial executors of diet-based microbial influence on the host. Here, we will review data supporting the di...
متن کاملGut microbial short-chain fatty acids in host defense and immune regulation
Our guts are inhabited by an enormous number of commensal bacteria, commonly referred to as the gut microbiota. Complex host-gut microbiota interactions are involved in the formation of the unique “gut ecosystem”. This ecosystem is thought to play a variety of roles in host physiology and pathology, including the modification and shaping of the host immune system. We have proposed an integrated...
متن کاملDietary and Microbial Metabolites in the Regulation of Host Immunity
Mucosal surfaces in the body, especially the intestine, are constantly exposed to trillions of microbiomes. Accumulating evidence has revealed that changes in the composition of the gut microbiome, especially that of the commensal bacteria population, are frequently associated with immunologic disorders. These changes coincide with changes in the production of certain dietary metabolites. Recen...
متن کاملGut microbial metabolite short-chain fatty acids and obesity
Over the past decade, the gut microbiota has emerged as an essential mediator in the pathophysiology of obesity and related metabolic disorders. In this context, the reciprocal interactions of the gut microbiota structure and their metabolite profiles with host metabolism predisposing to a range of pathological conditions (e.g., insulin resistance) related to energy homeostasis have been increa...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Lipid Nutrition
سال: 2015
ISSN: 1343-4594,1883-2237
DOI: 10.4010/jln.24.33